Breakthrough in microtubule research

Predicting Research Trends Identified by Research Histories via Breakthrough Researches

Since it is difficult to understand or predict research trends, we proposed methodologies for understanding and predicting research trends in the sciences, focusing on the structures of grants in the Japan Society for the Promotion of Science (JSPS), a Japanese funding agency. Grant applications are suitable for predicting research trends because these are research plans for the future, differe...

Multiyear Simulation Study Provides Breakthrough in Membrane Protein Research

Transgenic mouse models--a seminal breakthrough in oncogene research.

Transgenic mouse models are an integral part of modern cancer research, providing a versatile and powerful means of studying tumor initiation and progression, metastasis, and therapy. The present repertoire of these models is very diverse, with a wide range of strategies used to induce tumorigenesis by expressing dominant-acting oncogenes or disrupting the function of tumor-suppressor genes, of...

Review of The New ABCs of Research: Achieving Breakthrough Collaborations.

Solving the immense problems of the 21st century will require ambitious research teams that are skilled at producing practical solutions and foundational theories simultaneously – that is the ABC Principle: Applied & Basic Combined. Then these research teams can deliver high-impact outcomes by applying the SED Principle: Blend Science, Engineering and Design Thinking, which encourages use of th...

Steroids and endometrial breakthrough bleeding: future directions for research.

Abnormal endometrial bleeding continues to be a significant problem for women using long-acting gestagens and not only reduces the use of these agents, thus restricting the options available to women, but also reduces the quality of their lives. This symposium addressed a range of basic and clinical studies that have tried over the past 3 years to define the problem. Two areas have been identif...